For many APAC companies, expanding into new regions is a natural step toward growth. One market that’s increasingly catching attention is South America. With a strong digital economy and rising demand for B2B solutions, Latin America (LATAM) has many opportunities for companies. These companies can grow their customer base and achieve long-term success.
But breaking into a new region takes more than enthusiasm. You need the right partner, the right playbook, and the right strategy. This is where working with a cross-border marketing agency becomes invaluable.
By using local knowledge and global skills, APAC firms can grow their market in Latin America. They can also utilize LATAM Lead Generation Services to accelerate their growth.
In this guide, we will explore practical strategies for lead generation in South America. These strategies tackle the unique challenges of cross-border marketing. Let’s also discuss how APAC firms gain new clients and successfully expand into LATAM.
Want to grow your customer base in South America?
Why South America is a Prime Market for APAC Firms
South America is now one of the fastest-growing areas for digital use. Businesses and governments are using technology-driven solutions.
Brazil is experiencing a surge in SaaS adoption. Mexico has a strong need for fintech platforms. The cross-border market in LATAM is full of opportunities.
For APAC firms, expanding into this region offers three significant benefits:
- Access to a broader customer base with strong demand for B2B solutions.
- Opportunities to build LATAM B2B partnerships in fast-moving industries like fintech, SaaS, and logistics.
- A chance to diversify revenue and reduce reliance on existing APAC markets.
But entering South America without a plan can lead to common mistakes in cross-border marketing. To succeed, you must tailor your marketing cross-border strategies to align with local business practices and buyer expectations.
See how Callbox helped an Enterprise Manufacturing close more deals in the LATAM region.
APAC Lead Generation Strategies in South America
1. Personalize Your Marketing Per Country
While people often refer to South America as a single region, each country possesses unique characteristics.

For example:
- Brazil speaks Portuguese, while most other countries use Spanish.
- Business etiquette in Chile may differ from that in Colombia or Argentina.
That’s why your cross-border marketing strategy must prioritize country-level personalization. Instead of lumping them together, design campaigns for each country.
- Start with the larger economies like Brazil and Mexico, then expand into other countries as your resources grow.
- Tailor messaging to highlight specific use cases relevant to each country’s industries.
- Localize visuals, tone, and examples to resonate with local buyer personas.
Personalization not only strengthens trust but also enhances engagement and conversion, enabling APAC companies to expand their customer base effectively.
That’s how you can avoid significant challenges in cross-border marketing. It also shows prospects that you truly understand them.
Explore Top B2B Regions for Smarter Global Expansion
2. Use Native Writers and Cultural Experts
One of the easiest ways to lose credibility is through poor translations. Automated tools may save time, but they often create awkward or even incorrect phrasing.
To truly connect with your audience, you need to:
- Work with native writers and marketers who understand cultural sensitivities.
- Adapt thought leadership blogs, case studies, and email campaigns to each market.
- Use local expressions and examples that show authenticity and respect.
3. Prioritize Video and Mobile-First Campaigns
In South America, mobile is the dominant digital touchpoint. Buyers primarily consume their content via smartphones, and mobile internet penetration continues to increase.

This means you should design your campaigns with smartphone users in mind. Landing pages need to load fast, content should be easy to scan, and forms must be mobile-friendly.
At the same time, video has become a preferred medium for learning about new solutions. People are more likely to watch a product demo or customer story than read a long article. If you haven’t already, consider investing in short, engaging videos that explain your solution in Spanish or Portuguese. That’s one of the most effective ways to get new clients and build trust quickly.
4. Adapt Payments and Transaction Systems
Even in B2B markets, payment systems vary across South America. While global firms often default to credit cards, many LATAM businesses prefer localized payment options. For instance, Brazil relies heavily on Boleto Bancário, while Mexico favors OXXO payments.
If your offering involves subscriptions or recurring payments, supporting local options can remove a huge barrier for potential clients. It shows flexibility and a willingness to meet buyers on their terms.
5. Work with Local Experts or Outsource

Even the best in-house marketing team can struggle with the nuances of a new region. That’s why many APAC firms choose to partner with local agencies or hire specialists with experience in South America.
An outsourced team can give you instant access to:
- A multilingual sales development team that can connect with local decision-makers.
- Established databases of prospects and accounts in your target industries.
- Scalable lead generation campaigns without the high upfront cost of setting up local offices.
This approach helps you accelerate your LATAM expansion while avoiding the pitfalls that often accompany starting from scratch.
Speed up your market entry with our multilingual team and verified databases.
6. Adopt Multi-Channel Engagement for LATAM B2B Buyers
B2B buyers in South America, like those in APAC, conduct extensive research before speaking with a salesperson. To reach them effectively, you’ll need to show up across multiple touchpoints.
Here’s what works:
- Email campaigns with content tailored to each market.
- LinkedIn outreach to connect with decision-makers.
- Calls and instant messaging apps like WhatsApp for quicker engagement.
- Webinars and events to showcase expertise and connect directly.
This marketing strategy helps you be seen where your buyers are looking. It also makes it easier to keep conversations going.
7. Nurture Leads Through Structured Touchpoints
B2B lead generation doesn’t end after the first touchpoint. Many South American buyers involve multiple stakeholders, which extends the sales cycle. Without proper nurturing, even warm leads can slip away.

To maximize ROI, make sure to:
- Develop AI-powered lead nurture workflows with scheduled touchpoints across channels.
- Use content sequencing, case studies, ROI calculators, and industry reports to guide prospects through the funnel.
- Track buyer intent signals to re-engage dormant leads.
This long-term approach prevents wasted opportunities and ensures APAC firms sustain momentum in their LATAM B2B pipeline.
Overcoming Key Challenges in Cross-Border Marketing
Expanding into South America does come with hurdles, but none of these are deal-breakers if you’re prepared to face:
- Regulatory differences – Compliance varies across countries, particularly for data protection.
- Cultural misalignment – Misunderstanding business etiquette can slow negotiations.
- Operational hurdles – Time zones and logistics make customer support more complex.
Acknowledging these challenges in cross-border marketing early on allows you to adapt strategies and minimize risks. The key is to:
- Plan ahead
- Localize effectively
- Use the right partners to support your entry
By doing so, APAC companies can tap into a thriving region and build meaningful connections with LATAM buyers. This results in smoother execution of your LATAM expansion plans.
Final Thoughts
South America is one of the most promising regions for APAC firms ready to grow internationally.
Avoid common mistakes in cross-border marketing. Focus on localization, mobile-first engagement, and multichannel outreach. These strategies create a smoother path to lead generation in South America.
You don’t have to do everything in-house. A team with experience in the LATAM B2B landscape can help you expand your market reach faster. They also reduce risks and make sure your efforts deliver results.
In the end, the companies that succeed in LATAM expansion will be the ones that balance ambition with smart, localized strategies. That’s how you’ll win new clients and establish a strong foothold in this exciting market.





